HTRA4 Polyclonal Antibody

Background:
This gene encodes a member of the HtrA family of proteases. The encoded protein contains a putative signal peptide, an insulin growth factor binding domain, a Kazal protease inhibitor domain, a conserved trypsin domain and a PDZ domain. Based on studies on other related family members, this enzyme may function as a secreted oligomeric chaperone protease to degrade misfolded secretory proteins. Other human HtrA proteins have been implicated in arthritis, tumor suppression, unfolded stress response, apoptosis, and aging.

Research Area: Cell Biology

Synonyms:
FLJ90724, High temperature requirement protean A4, High-temperature requirement factor A4, HTRA 4, HtrA serine peptidase 4, HTRA4, HTRA4, Probable serine protease HTRA4, Serine protease HTRA4

Immunogen: Synthetic peptide of human HTRA4

Swissprot: P83105
Gene Accession: NP710159

Calculated MW: 51 kDa
Observed MW: Refer to figures

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.