Human AMPK beta 2 (PRKAB2) (clone 6G1) DyLight® 550, anti-human
€600.00
In stock
SKU
AC-ABO14812
Description: Anti-Human AMPK beta 2 DyLight® 550 conjugated PRKAB2 Antibody (monoclonal, 6G1) . Tested in Flow Cytometry applications. This antibody reacts with Human.
Protein Function:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Other Names: 5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2, PRKAB2
Clone Name(s):
Clone: 6G1
Gene ID: 5565
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human AMPK beta 2, different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.
Calculated MW: 30302
Format: Liquid
Contents: Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Concentration (mg/ml): 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Protein Function:
Non-catalytic subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Beta non-catalytic subunit acts as a scaffold on which the AMPK complex assembles, via its C-terminus that bridges alpha (PRKAA1 or PRKAA2) and gamma subunits (PRKAG1, PRKAG2 or PRKAG3).
Other Names: 5'-AMP-activated protein kinase subunit beta-2, AMPK subunit beta-2, PRKAB2
Clone Name(s):
Clone: 6G1
Gene ID: 5565
Immunogen: A synthetic peptide corresponding to a sequence at the N-terminus of human AMPK beta 2, different from the related mouse sequence by three amino acids, and from the related rat sequence by two amino acids.
Calculated MW: 30302
Format: Liquid
Contents: Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN3.
Concentration (mg/ml): 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
| Is Featured? | No |
|---|
Write Your Own Review