Human Cardiac Troponin I Recombinant Protein (Active)
€0.00
In stock
SKU
BRP1090
Description: Recombinant full length human cardiac Troponin I protein.
Background:
Troponin I is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle, the others are troponin T and troponin C. Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. It binds actin and inhibits actomyosin ATPase activity in the absence of calcium. In 2000, Labarrere et al. found that persistent elevation of cardiac troponin I levels after heart transplantation were associated with high risk for developing coronary artery disease and graft failure after cardiac transplantation. The cardiac troponin I may be a useful tool in identifying patients with heart failure who are at increased risk for progressive ventricular dysfunction and death.
Synonyms:
Troponin I, cardiac muscle, TnIc, Cardiac Troponin I, cTnI, TNNI3, TNNC1
Purity: >95% by SDS-PAGE
Storage buffer: Each vial contains 10 mM PBS(pH7.4) without preservative.
Storage and Expiration:
Ship at 4℃.Upon receipt, aliquot and store at -20℃ or -80℃ for long term. Avoid repeated freeze and thaw cycles.
Background:
Troponin I is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle, the others are troponin T and troponin C. Human troponin I is presented in cardiac muscle tissue by a single isoform with molecular weight 23876 Da and it consists of 209 amino acid residues. It binds actin and inhibits actomyosin ATPase activity in the absence of calcium. In 2000, Labarrere et al. found that persistent elevation of cardiac troponin I levels after heart transplantation were associated with high risk for developing coronary artery disease and graft failure after cardiac transplantation. The cardiac troponin I may be a useful tool in identifying patients with heart failure who are at increased risk for progressive ventricular dysfunction and death.
Synonyms:
Troponin I, cardiac muscle, TnIc, Cardiac Troponin I, cTnI, TNNI3, TNNC1
Purity: >95% by SDS-PAGE
Storage buffer: Each vial contains 10 mM PBS(pH7.4) without preservative.
Storage and Expiration:
Ship at 4℃.Upon receipt, aliquot and store at -20℃ or -80℃ for long term. Avoid repeated freeze and thaw cycles.
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