Human CD46 (clone 9E9)DyLight® 488, anti-human
€600.00
In stock
SKU
AC-ABO14931
Description: Anti-Human CD46 DyLight® 488 conjugated Antibody (monoclonal, 9E9) . Tested in Flow Cytometry applications. This antibody reacts with Human.Protein Name: Membrane cofactor protein
Protein Function:
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Other Names: Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, CD46, MCP, MIC10
Clone Name(s):
Clone: 9E9
Gene ID: 4179
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CD46.
Calculated MW: 43747
Format: Liquid
Contents: Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN5.
Concentration (mg/ml): 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Protein Function:
Acts as a cofactor for complement factor I, a serine protease which protects autologous cells against complement-mediated injury by cleaving C3b and C4b deposited on host tissue. May be involved in the fusion of the spermatozoa with the oocyte during fertilization. Also acts as a costimulatory factor for T-cells which induces the differentiation of CD4+ into T-regulatory 1 cells. T-regulatory 1 cells suppress immune responses by secreting interleukin-10, and therefore are thought to prevent autoimmunity.
Other Names: Membrane cofactor protein, TLX, Trophoblast leukocyte common antigen, CD46, CD46, MCP, MIC10
Clone Name(s):
Clone: 9E9
Gene ID: 4179
Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human CD46.
Calculated MW: 43747
Format: Liquid
Contents: Each vial contains 50% glycerol, 0.9% NaCl, 0.2% Na2HPO4, 0.02% NaN5.
Concentration (mg/ml): 0.5-1mg/ml, actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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