Human COPE (clone 9B6) DyLight® 488, anti-human
€600.00
In stock
SKU
AC-ABO14907
Description: Anti-Human COPE DyLight® 488 conjugated Antibody (monoclonal, 9B6) . Tested in Flow Cytometry applications. This antibody reacts with Human.
Protein Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Other Names: Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP, COPE
Clone Name(s):
Clone: 9B6
Tissue Specificity: Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side; Cytoplasm; COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side;
Gene ID: 11316
Immunogen: E.coli-derived human COPE recombinant protein (Position: E80-A308). Human COPE shares 89.5% amino acid (aa) sequence identity with mouse COPE.
Calculated MW: 34482
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Protein Function:
The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. The coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated with ADP-ribosylation factors (ARFs), which are small GTP-binding proteins; the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors (By similarity).
Other Names: Coatomer subunit epsilon, Epsilon-coat protein, Epsilon-COP, COPE
Clone Name(s):
Clone: 9B6
Tissue Specificity: Golgi apparatus membrane; Peripheral membrane protein; Cytoplasmic side; Cytoplasm; COPI-coated vesicle membrane; Peripheral membrane protein; Cytoplasmic side;
Gene ID: 11316
Immunogen: E.coli-derived human COPE recombinant protein (Position: E80-A308). Human COPE shares 89.5% amino acid (aa) sequence identity with mouse COPE.
Calculated MW: 34482
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
| Is Featured? | No |
|---|
Write Your Own Review