Human Fatty Acid Binding Recombinant Protein 3, FABP3 Recombinant Protein (Active)
€0.00
In stock
SKU
BRP1013
Description: Recombinant full length human FABP protein with molecular weight 15 kDa.
Background:
Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain. It is also the biomarker for heart injury. In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.
Synonyms:
Fattyacid-binding protein 3, FABP3, Heart-type fatty acid-binding protein, H-FABP, Mammary-derived growth inhibitor, MDGI, Muscle fatty acid-binding protein, M-FABP, FABP11
Purity: >95% by SDS-PAGE
Storage buffer: Each vial contains 20 mM Tris-HCL, 140 mM NaCl, 2 mM EDTA(pH8.0) without preservative.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term. Avoid repeated freeze and thaw cycles.
Background:
Heart-type fatty acid binding protein (hFABP) also known as mammary-derived growth inhibitor is a protein that in humans is encoded by the FABP3 gene. It is a small cytoplasmic protein (15 kDa) released from cardiac myocytes following an ischemic episode. Like the nine other distinct FABPs that have been identified, H-FABP is involved in active fatty acid metabolism where it transports fatty acids from the cell membrane to mitochondria for oxidation. H-FABP is a sensitive biomarker for myocardial infarction and can be detected in the blood within one to three hours of the pain. It is also the biomarker for heart injury. In addition to its diagnostic potential, H-FABP also has prognostic value. Alongside D-dimer, NT-proBNP and peak troponin T, it was the only cardiac biomarker that proved to be a statistically significant predictor of death or Mi at one year.
Synonyms:
Fattyacid-binding protein 3, FABP3, Heart-type fatty acid-binding protein, H-FABP, Mammary-derived growth inhibitor, MDGI, Muscle fatty acid-binding protein, M-FABP, FABP11
Purity: >95% by SDS-PAGE
Storage buffer: Each vial contains 20 mM Tris-HCL, 140 mM NaCl, 2 mM EDTA(pH8.0) without preservative.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ or -80℃ for long term. Avoid repeated freeze and thaw cycles.
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