Human FGF acidic / FGF1 Recombinant Protein (Active)
€0.00
In stock
SKU
BRP1018
Description: Recombinant human FGF acidic / FGF1 protein with molecular weight 15.3kDa.
Background:
Fibroblast growth factor, acidic (FGFA) also know as Fibroblast growth factor 1 (FGF1) isexpressed in the proliferative and hypertrophic zones of human cartilage.Itis the prototype of the 22-member FGF family of proteins and has been implicated in a range of physiological processes, including development, wound healing and cardiovascular changes.The intracellular mammalian FGF1 was phosphorylated on a single phosphorylation site (ser130), and that phosphorylation occurred in the nucleus following activation and nuclear import of protein kinase C-delta (PRKCD). Phosphorylated FGF1 was then exported to the cytosol via exportin-1 (XPO1).
Synonyms:
Fibroblast growth factor 1, FGF1, Acidic fibroblast growth factor, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1, HBGF-1, FGFA
Purity: >95% by SDS-PAGE
Endotoxin level: < 0.1 ng/μg (1 EU/μg) by LAL test
Reconstitution: Reconstitute with sterile 18MΩ-cm H2O.
Dimers: < 1% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Phosphate bufferand 200 mM NaCl(pH7.0) without preservatives.
Storage and Expiration:
Ship at 4℃. Upon receipt, store at -20℃ or -80℃ for long term. After reconstituting, it can store at 4℃ for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze and thaw cycles.
Background:
Fibroblast growth factor, acidic (FGFA) also know as Fibroblast growth factor 1 (FGF1) isexpressed in the proliferative and hypertrophic zones of human cartilage.Itis the prototype of the 22-member FGF family of proteins and has been implicated in a range of physiological processes, including development, wound healing and cardiovascular changes.The intracellular mammalian FGF1 was phosphorylated on a single phosphorylation site (ser130), and that phosphorylation occurred in the nucleus following activation and nuclear import of protein kinase C-delta (PRKCD). Phosphorylated FGF1 was then exported to the cytosol via exportin-1 (XPO1).
Synonyms:
Fibroblast growth factor 1, FGF1, Acidic fibroblast growth factor, aFGF, Endothelial cell growth factor, ECGF, Heparin-binding growth factor 1, HBGF-1, FGFA
Purity: >95% by SDS-PAGE
Endotoxin level: < 0.1 ng/μg (1 EU/μg) by LAL test
Reconstitution: Reconstitute with sterile 18MΩ-cm H2O.
Dimers: < 1% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Phosphate bufferand 200 mM NaCl(pH7.0) without preservatives.
Storage and Expiration:
Ship at 4℃. Upon receipt, store at -20℃ or -80℃ for long term. After reconstituting, it can store at 4℃ for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze and thaw cycles.
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