Human Insulin-like growth factors-2,IGF2 Recombinant Protein
€0.00
In stock
SKU
BRP1113
Description: Recombinant human IGF2 protein.
Background:
Insulin-like growth factor 2 (IGF-2), also called somatomedin A, is a member of the insulin family of polypeptide growth factors. It is also one of three protein hormones that share structural similarity to insulin. In humans, the IGF2 gene is located on chromosome 11p15.5, extends over 30 kb and contains 8 exons. Scott et al. (1985) found that expression of the IGF2 gene was markedly increased relative to adult tissues, but was comparable to the level of expression in several fetal tissues including kidney, liver, adrenal, and striated muscle. Its functions include mediation of growth hormone action, stimulation of growth of cultured cells, stimulation of the action of insulin, and involvement in development and growth.
Synonyms:
Insulin-like growth factor II, IGF2, IGF-II, Somatomedin-A, T3M-11-derived growth factor, Insulin-like growth factor II Ala-25 Del, Preptin, PP1446, IGF-2.
Purity: > 90% by SDS-PAGE
Storage buffer: Each vial contains 10 mM PBS, pH 7.4±0.2 with 0.1% SKL as the preservative.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term. Avoid repeated freeze and thaw cycles.
Background:
Insulin-like growth factor 2 (IGF-2), also called somatomedin A, is a member of the insulin family of polypeptide growth factors. It is also one of three protein hormones that share structural similarity to insulin. In humans, the IGF2 gene is located on chromosome 11p15.5, extends over 30 kb and contains 8 exons. Scott et al. (1985) found that expression of the IGF2 gene was markedly increased relative to adult tissues, but was comparable to the level of expression in several fetal tissues including kidney, liver, adrenal, and striated muscle. Its functions include mediation of growth hormone action, stimulation of growth of cultured cells, stimulation of the action of insulin, and involvement in development and growth.
Synonyms:
Insulin-like growth factor II, IGF2, IGF-II, Somatomedin-A, T3M-11-derived growth factor, Insulin-like growth factor II Ala-25 Del, Preptin, PP1446, IGF-2.
Purity: > 90% by SDS-PAGE
Storage buffer: Each vial contains 10 mM PBS, pH 7.4±0.2 with 0.1% SKL as the preservative.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term. Avoid repeated freeze and thaw cycles.
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