Human Interleukin-1 alpha, IL1A Recombinant Protein
€0.00
In stock
SKU
BRP1116
Description: Recombinant human IL-1 alpha protein.
Background:
Interleukin-1 alpha (IL-1α) is a protein of the interleukin-1 family that in humans is encoded by the IL1A gene which spans 10.2 kb and has 7 exons. It is 1 of 2 structurally distinct forms of IL1, the other being IL1B, this two proteins are synthesized by a variety of cell types, including activated macrophages, keratinocytes, stimulated B lymphocytes, and fibroblasts, and are potent mediators of inflammation and immunity. IL1A may play a role in the genesis of inflammation by augmenting the transcription of proinflammatory genes, a mechanism not affected by extracellular inhibitors. IL1A has been administered to patients during receiving autologous bone marrow transplantation.
Synonyms:
Interleukin-1 alpha, IL1A, IL-1 alpha, Hematopoietin-1, IL1F1, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha.
Purity: >90% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Tris-HCl, pH 7.4±0.2.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term. Avoid repeated freeze and thaw cycles.
Background:
Interleukin-1 alpha (IL-1α) is a protein of the interleukin-1 family that in humans is encoded by the IL1A gene which spans 10.2 kb and has 7 exons. It is 1 of 2 structurally distinct forms of IL1, the other being IL1B, this two proteins are synthesized by a variety of cell types, including activated macrophages, keratinocytes, stimulated B lymphocytes, and fibroblasts, and are potent mediators of inflammation and immunity. IL1A may play a role in the genesis of inflammation by augmenting the transcription of proinflammatory genes, a mechanism not affected by extracellular inhibitors. IL1A has been administered to patients during receiving autologous bone marrow transplantation.
Synonyms:
Interleukin-1 alpha, IL1A, IL-1 alpha, Hematopoietin-1, IL1F1, IL-1A, IL1, IL1-ALPHA, IL1F1, interleukin 1 alpha.
Purity: >90% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Tris-HCl, pH 7.4±0.2.
Storage and Expiration:
Ship at 4℃. Upon receipt, aliquot and store at -20℃ for long term. Avoid repeated freeze and thaw cycles.
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