Human Interleukin-2, IL-2 Recombinant Protein (Active)
€0.00
In stock
SKU
BRP1040
Description: Recombinant human IL-2 protein with molecular weight 15 kDa.
Background:
Interleukin-2 (IL2), formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. It is produced not only by mature T lymphocytes on stimulation but also constitutively by certain T-cell lymphoma cell lines. IL-2 expression in mature thymocytes and T cells has been found to be tightly controlled by monoallelic expression. It can act as a growth hormone for both B and T lymphocytes. IL-2 has a well documented role in induction of pruritus, furthermore, it has been found to be higher in pruritic lesions of psoriasis compared to non-pruritic ones.
Synonyms:
Interleukin-2, IL-2, T-cell growth factor, TCGF, Aldesleukin
Purity: >95% by SDS-PAGE
Endotoxin level: < 0.1 ng/μg (1 EU/μg) by LAL test
Reconstitution: Reconstitute with sterile 18MΩ-cm H2O.
Dimers: < 1% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Phosphate bufferand 200 mM NaCl(pH7.0) without preservatives.
Storage and Expiration:
Ship at 4℃. Upon receipt, store at -20℃ or -80℃ for 2 years. After reconstituting, it can store at 4℃ for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze and thaw cycles.
Background:
Interleukin-2 (IL2), formerly referred to as T-cell growth factor, is a powerfully immunoregulatory lymphokine that is produced by lectin- or antigen-activated T cells. It is produced not only by mature T lymphocytes on stimulation but also constitutively by certain T-cell lymphoma cell lines. IL-2 expression in mature thymocytes and T cells has been found to be tightly controlled by monoallelic expression. It can act as a growth hormone for both B and T lymphocytes. IL-2 has a well documented role in induction of pruritus, furthermore, it has been found to be higher in pruritic lesions of psoriasis compared to non-pruritic ones.
Synonyms:
Interleukin-2, IL-2, T-cell growth factor, TCGF, Aldesleukin
Purity: >95% by SDS-PAGE
Endotoxin level: < 0.1 ng/μg (1 EU/μg) by LAL test
Reconstitution: Reconstitute with sterile 18MΩ-cm H2O.
Dimers: < 1% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Phosphate bufferand 200 mM NaCl(pH7.0) without preservatives.
Storage and Expiration:
Ship at 4℃. Upon receipt, store at -20℃ or -80℃ for 2 years. After reconstituting, it can store at 4℃ for a week, it is recommended to add 0.1% HSA or BSA for long term. Avoid repeated freeze and thaw cycles.
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