Human IRS1 (clone 10I3) DyLight® 488, anti-human
€600.00
In stock
SKU
AC-ABO14906
Description: Anti-Human IRS1 DyLight® 488 conjugated Antibody (monoclonal, 10I3) . Tested in Flow Cytometry applications. This antibody reacts with Human.
Protein Function:
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
Other Names: Insulin receptor substrate 1, IRS-1, Irs1, Irs-1
Clone Name(s):
Clone: 10I3
Subcellular Localization: ciliary basal body; cytosol; nucleus; caveola; insulin receptor complex; plasma membrane; cytoplasm; intracellular membrane-bounded organelle; Complete GO annotation on QuickGO
Tissue Specificity: Expressed in osteoblasts, but not in osteoclasts.
Gene ID: 16367
Immunogen: E.coli-derived human IRS1 recombinant protein (Position: S1041-Q1242). Human IRS1 shares 78% and 80% amino acid (aa) sequence identity with mouse and rat IRS1, respectively.
Calculated MW: 130723
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
Protein Function:
May mediate the control of various cellular processes by insulin. When phosphorylated by the insulin receptor binds specifically to various cellular proteins containing SH2 domains such as phosphatidylinositol 3-kinase p85 subunit or GRB2. Activates phosphatidylinositol 3-kinase when bound to the regulatory p85 subunit (By similarity).
Other Names: Insulin receptor substrate 1, IRS-1, Irs1, Irs-1
Clone Name(s):
Clone: 10I3
Subcellular Localization: ciliary basal body; cytosol; nucleus; caveola; insulin receptor complex; plasma membrane; cytoplasm; intracellular membrane-bounded organelle; Complete GO annotation on QuickGO
Tissue Specificity: Expressed in osteoblasts, but not in osteoclasts.
Gene ID: 16367
Immunogen: E.coli-derived human IRS1 recombinant protein (Position: S1041-Q1242). Human IRS1 shares 78% and 80% amino acid (aa) sequence identity with mouse and rat IRS1, respectively.
Calculated MW: 130723
Purification: Immunogen affinity purified.
Format: Lyophilized
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500 µg/ml.
Contents: Each vial contains 4mg Trehalose, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg NaN3.
Storage: At -20°C for one year from date of receipt. Avoid repeated freezing and thawing. Protect from light.
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