Human MSLN(296-580) Protein, mFc-His Tag

Human MSLN(296-580) Protein, mFc-His Tag

€403.00
In stock
SKU
PME100031
Catalog Number: PME100031
Size: 100 μg
Datasheet
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Description: Recombinant human MSLN(296-580) protein with C-terminal mouse Fc and 6×His tag

Background:
This gene encodes a preproprotein that is proteolytically processed to generate two protein products, megakaryocyte potentiating factor and mesothelin. Megakaryocyte potentiating factor functions as a cytokine that can stimulate colony formation of bone marrow megakaryocytes. Mesothelin is a glycosylphosphatidylinositol-anchored cell-surface protein that may function as a cell adhesion protein. This protein is overexpressed in epithelial mesotheliomas, ovarian cancers and in specific squamous cell carcinomas. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Synonyms: MSLN, Mesothelin, MPF

Molecular Weight: The protein has a predicted molecular mass of 59.3 kDa after removal of the signal peptide.

Purity: The purity of the protein is greater than 95% as determined by SDS-PAGE and Coomassie blue staining.

Buffer: PBS, pH7.4

Buffer: Store at -80°C for 12 months (Avoid repeated freezing and thawing)

Usage: Research use only
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