Human Osteopontin, OPN Recombinant Protein (Active)
€0.00
In stock
SKU
BRP1071
Description: Recombinant full length human OPN protein with molecular weight 35 kDa.
Background:
Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), secreted phosphoprotein 1 (SPP1), is a human gene product. The gene has 7 exons, spans 5 kilobases in length and in humans it is located on 4q13. The protein is composed of ~300 amino acids residues and has ~30 carbohydrate residues attached including 10 sialic acid residues, which are attached to the protein during post-translational modification in the Golgi apparatus. Osteopontin has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones.
Synonyms:
Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, SPP1, Urinary stone protein, Uropontin, BNSP, OPN, BSPI, ETA-1
Purity: >95% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Tris-HCl (pH7.4±0.2) with 0.2% NaN3.
Storage and Expiration:
Ship at 4℃.Upon receipt, aliquot and store at -20℃ or -80℃ for long term. Avoid repeated freeze and thaw cycles.
Background:
Osteopontin (OPN), also known as bone sialoprotein I (BSP-1 or BNSP), secreted phosphoprotein 1 (SPP1), is a human gene product. The gene has 7 exons, spans 5 kilobases in length and in humans it is located on 4q13. The protein is composed of ~300 amino acids residues and has ~30 carbohydrate residues attached including 10 sialic acid residues, which are attached to the protein during post-translational modification in the Golgi apparatus. Osteopontin has been implicated as an important factor in bone remodeling. Specifically, research suggests it plays a role in anchoring osteoclasts to the mineral matrix of bones.
Synonyms:
Bone sialoprotein 1, Nephropontin, Secreted phosphoprotein 1, SPP1, Urinary stone protein, Uropontin, BNSP, OPN, BSPI, ETA-1
Purity: >95% by SDS-PAGE
Storage buffer: Each vial contains 10 mM Tris-HCl (pH7.4±0.2) with 0.2% NaN3.
Storage and Expiration:
Ship at 4℃.Upon receipt, aliquot and store at -20℃ or -80℃ for long term. Avoid repeated freeze and thaw cycles.
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