Human Type I Hair Keratin K39 polyclonal, anti-human, mouse

Quantity: 25 µl

Background:
This gene encodes a member of the type I (acidic) keratin family, which belongs to the superfamily of intermediate filament (IF) proteins. Keratins are heteropolymeric structural proteins which form the intermediate filament. These filaments, along with actin microfilaments and microtubules, compose the cytoskeleton of epithelial cells. The type I keratin genes are clustered in a region of chromosome 17q12-q21.

Synonyms:
KRT39, K39, KA35, CK-39

Isotype: Guinea pig Polyclonal (K26am.1)

Immunogen:
Synthetic peptide of human type I (acidic) hair (trichocytic) keratin K39 (former designation keratin Ka35): DTKGCTTTNSPSTP, coupled to KLH

Form: Stabilized Serum

Specificity:
The antiserum stains specifically human hair keratin K39 expressed in the late hair cortex and late cuticle.

Reactivity: human, mouse

Applications: Suitable for Immunofluorescence microscopy on frozen sections, Immunohistochemistry on paraffin sections, only when using the microwave method (citrate buffer)

Working DIlution: 1 : 100 for immunohistochemistry.

Storage: 2-8C

References:
- Langbein L et al. (2007) J Invest Dermatol 127: 1532-1535