HVEM/TNFRSF14 Polyclonal Antibody

Background:
This gene encodes a member of the TNF (tumor necrosis factor) receptor superfamily. The encoded protein functions in signal transduction pathways that activate inflammatory and inhibitory T-cell immune response. It binds herpes simplex virus (HSV) viral envelope glycoprotein D (gD), mediating its entry into cells. Alternative splicing results in multiple transcript variants.

Research Area: Cancer, Immunology, Signal Transduction

Synonyms:
TNFRSF14, ATAR, CD270, HVEA, HVEM, LIGHTR, TR2

Immunogen: Recombinant fusion protein of human HVEM/TNFRSF14 (NP_003811.2).

Swissprot: Q92956
Gene ID: 8764

Calculated MW: 21 kDa/30 kDa
Observed MW: 30 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.