HXK I / HK1 (clone ), anti-human
€388.00
In stock
SKU
MB0140
Background:
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alternative Name:
Hexokinase-1, Hexokinase 1, Brain form hexokinase, Hexokinase type I, HK I, HK1
Application Dilution: WB: 1:1000~10000, ICC: 1:100~500
Specificity: This antibody detects endogenous levels of Hexokinase-1 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human HXK I.
MW: Predicted band size: 102kDa , Observed band size: 102kDa
Swis Prot.: P19367
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of hexokinase which localizes to the outer membrane of mitochondria. Mutations in this gene have been associated with hemolytic anemia due to hexokinase deficiency. Alternative splicing of this gene results in five transcript variants which encode different isoforms, some of which are tissue-specific. Each isoform has a distinct N-terminus; the remainder of the protein is identical among all the isoforms. A sixth transcript variant has been described, but due to the presence of several stop codons, it is not thought to encode a protein.
Alternative Name:
Hexokinase-1, Hexokinase 1, Brain form hexokinase, Hexokinase type I, HK I, HK1
Application Dilution: WB: 1:1000~10000, ICC: 1:100~500
Specificity: This antibody detects endogenous levels of Hexokinase-1 and does not cross-react with related proteins
Immunogen:
Recombinant full length Human HXK I.
MW: Predicted band size: 102kDa , Observed band size: 102kDa
Swis Prot.: P19367
Purification & Purity:
The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
Purified mouse monoclonal in buffer containing 0.1M Tris-Glycine (pH 7.4, 150 mM NaCl) with 0.2% sodium azide, 50%,glycerol
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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