HXK III polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS71222
Background:
Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.
Alternative Name:
HXK3, HKIII, Hexokinase-3, Hexokinase 3, Hexokinase3,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: HXK III polyclonal antibody detects endogenous levels of HXK III protein.
Immunogen:
Recombinant protein of human HK3.
MW: ~ 99 kDa
Swis Prot.: P52790
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
Hexokinases phosphorylate glucose to produce glucose 6 phosphate, thus committing glucose to the glycolytic pathway. In vertebrates there are four major glucose phosphorylating isoenzymes, designated hexokinase I, II, III and IV (glucokinase). Similar to hexokinases I and II, the allosteric enzyme hexokinase III is inhibited by its product glucose 6 phosphate. The catalytic activity of hexokinase III is associated with the C terminus while regulatory function is associated with the N terminus.
Alternative Name:
HXK3, HKIII, Hexokinase-3, Hexokinase 3, Hexokinase3,
Application Dilution: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200
Specificity: HXK III polyclonal antibody detects endogenous levels of HXK III protein.
Immunogen:
Recombinant protein of human HK3.
MW: ~ 99 kDa
Swis Prot.: P52790
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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