HYAL1 antibody (clone 2H7), anti-human
€435.00
In stock
SKU
AC-AT2461a
Catalog Number: AC-AT2461a
Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E, IP
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Size: 100 µg
Isotype: mouse IgG2a Kappa
Applications: E, IP
Request Information AC-AT2461a">Request Information
Background:
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, LUCA1
Antigen Type:
Recombinant Protein
Gene Name: HYAL1
Gene ID: 3373
NCBI Accession: NP_149349.2;NP_695013.1;NP_695014.1;NP_695015.1;NP_695017.1
Primary Accession: Q12794
Other Accession: NM_007312
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.
Other Names:
Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, LUCA1
Antigen Type:
Recombinant Protein
Gene Name: HYAL1
Gene ID: 3373
NCBI Accession: NP_149349.2;NP_695013.1;NP_695014.1;NP_695015.1;NP_695017.1
Primary Accession: Q12794
Other Accession: NM_007312
Format: Clear, colorless solution in phosphate buffered saline, pH 7.2 .
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