HYAL1 polyclonal, anti-mouse

Quantity: 100 µg

Background:
Hyaluronidase-1, also known as HYAL1 or LUCA1, is an enzyme that in humans is encoded by the HYAL1 gene. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency.

Description:
Rabbit IgG polyclonal antibody for Hyaluronidase-1 (HYAL1) detection. Tested with WB in mouse.

Synonyms:
HYAL 1 antibody, Hyal-1 antibody, HYAL1 antibody, HYAL1_HUMAN antibody, Hyaluronidase 1 antibody, Hyaluronidase-1 antibody, Hyaluronoglucosaminidase 1 antibody, Hyaluronoglucosaminidase-1 antibody, Hyaluronoglucosaminidase1 antibody, LUCA 1 antibody, LUCA-1 antibody, LUCA1 antibody, Lung carcinoma protein 1 antibody, MGC45987 antibody, NAT6 antibody, Plasma hyaluronidase antibody, Tumor suppressor LUCA 1 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of mouse HYAL1(434-450aa LKDRAQMAMKFRCRCYR), different from the related rat sequence by one amino acid.A synthetic peptide corresponding to a sequence at the C-terminus of mouse HYAL1(434-450aa LKDRAQMAMKFRCRCYR), different from the related rat sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: mouse

Applications: WB

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.