HYAL1 polyclonal (C-term), anti-human

HYAL1 polyclonal (C-term), anti-human

€0.00
In stock
SKU
AC-AP14886b
Catalog Number: AC-AP14886b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB35190
Applications: IHC-P, WB
Datasheet

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Background:
This gene encodes a lysosomal hyaluronidase. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is thought to be involved in cell proliferation, migration and differentiation. This enzyme is active at an acidic pH and is the major hyaluronidase in plasma. Mutations in this gene are associated with mucopolysaccharidosis type IX, or hyaluronidase deficiency. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression. Multiple transcript variants encoding different isoforms have been found for this gene.

Other Names:
Hyaluronidase-1, Hyal-1, Hyaluronoglucosaminidase-1, Lung carcinoma protein 1, LuCa-1, HYAL1, LUCA1

Target/Specificity:
This HYAL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 280-309 amino acids from the C-terminal region of human HYAL1.

Antigen Region:
280-309

Antigen Type: Synthetic Peptide

Gene Name: HYAL1
Gene ID: 3373
Primary Accession: Q12794
NCBI Accession: NP_149349.2;NP_695013.1;NP_695014.1;NP_695015.1;NP_695017.1
Other Accession: NP_695013.1;NP_695017.1;NP_009296.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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