HYAL2 Antibody (Center) Blocking peptide
€363.00
In stock
SKU
AC-BP12491c
Background:
This gene encodes a weak acid-active hyaluronidase. Theencoded protein is similar in structure to other more activehyaluronidases. Hyaluronidases degrade hyaluronan, one of the majorglycosaminoglycans of the extracellular matrix. Hyaluronan andfragments of hyaluronan are thought to be involved in cellproliferation, migration and differentiation. Although it waspreviously thought to be a lysosomal hyaluronidase that is activeat a pH below 4, the encoded protein is likely a GPI-anchored cellsurface protein. This hyaluronidase serves as a receptor for theoncogenic virus Jaagsiekte sheep retrovirus. The gene is one ofseveral related genes in a region of chromosome 3p21.3 associatedwith tumor suppression. This gene encodes two alternatively splicedtranscript variants which differ only in the 5' UTR.
Other Names:
Hyaluronidase-2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2, LuCa-2, HYAL2, LUCA2
Gene Name: HYAL2
Gene ID: 8692
Primary Accession: Q12891
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
This gene encodes a weak acid-active hyaluronidase. Theencoded protein is similar in structure to other more activehyaluronidases. Hyaluronidases degrade hyaluronan, one of the majorglycosaminoglycans of the extracellular matrix. Hyaluronan andfragments of hyaluronan are thought to be involved in cellproliferation, migration and differentiation. Although it waspreviously thought to be a lysosomal hyaluronidase that is activeat a pH below 4, the encoded protein is likely a GPI-anchored cellsurface protein. This hyaluronidase serves as a receptor for theoncogenic virus Jaagsiekte sheep retrovirus. The gene is one ofseveral related genes in a region of chromosome 3p21.3 associatedwith tumor suppression. This gene encodes two alternatively splicedtranscript variants which differ only in the 5' UTR.
Other Names:
Hyaluronidase-2, Hyal-2, Hyaluronoglucosaminidase-2, Lung carcinoma protein 2, LuCa-2, HYAL2, LUCA2
Gene Name: HYAL2
Gene ID: 8692
Primary Accession: Q12891
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
| Is Featured? | No |
|---|
Write Your Own Review