HYAL3 polyclonal, anti-human, mouse

Quantity: 100 µg

Background:
HYAL3(hyaluronoglucosaminidase 3) is an enzyme that in humans is encoded by the HYAL3 gene, also known as LUCA3, Hyaluronidase-3, Lung carcinoma protein 3, LUCA-3, LUCA14, Minna14. By Northern blot analysis, expression of a 2.1-kb HYAL3 transcript that was strongest in testis and bone marrow, but relatively weak in other organs. HYAL3 encodes a predicted 417-amino acid protein. This gene encodes a protein which is similar in structure to hyaluronidases. Hyaluronidases intracellularly degrade hyaluronan, one of the major glycosaminoglycans of the extracellular matrix. Hyaluronan is though to be involved in cell proliferation, migration and differentiation. However, this protein has not yet been shown to have hyaluronidase activity. The gene is one of several related genes in a region of chromosome 3p21.3 associated with tumor suppression.

Description:
Rabbit IgG polyclonal antibody for Hyaluronidase-3 (HYAL3) detection. Tested with WB, IHC-P in Human, Mouse.

Synonyms:
Hyal-3 antibody, HYAL3 antibody, HYAL3_HUMAN antibody, Hyaluronidase 3 antibody, Hyaluronidase-3 antibody, Hyaluronoglucosaminidase 3 antibody, Hyaluronoglucosaminidase-3 antibody, LUCA-3 antibody, LUCA14 antibody, LUCA3 antibody, Lung carcinoma protein 3 antibody, Minna14 antibody

Isotype: Rabbit polyclonal IgG

Immunogen:
A synthetic peptide corresponding to a sequence at the C-terminus of human HYAL3(357-371aa SHQRCHGHGRCARRD), different from the related rat sequence by three amino acids, and different from the related mouse sequence by one amino acid.

Form: Lyophilized; Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.

Specificity:
No cross reactivity with other proteins.

Reactivity: Reacts with: human.
Predicted to work with: mouse.

Applications: WB, IHC-P

Reconstitution:
Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Storage: At -20˚C for one year. After reconstitution, at 4˚C for one month. It can also be aliquotted and stored frozen at -20˚C for a longer time. Avoid repeated freezing and thawing.