IARS Antibody (N-term) Blocking Peptide
€363.00
In stock
SKU
AC-BP7845a
Background:
Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. It catalyzes the chemical reaction:ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
Other Names:
Isoleucine--tRNA ligase, cytoplasmic, Isoleucyl-tRNA synthetase, IRS, IleRS, IARS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7845a was selected from the N-term region of human IARS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IARS1 (HGNC:5330)
Gene ID: 3376
Primary Accession: P41252
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Isoleucine-tRNA synthetase belongs to the class-I aminoacyl-tRNA synthetase family and has been identified as a target of autoantibodies in the autoimmune disease polymyositis/dermatomyositis. It catalyzes the chemical reaction:ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile).
Other Names:
Isoleucine--tRNA ligase, cytoplasmic, Isoleucyl-tRNA synthetase, IRS, IleRS, IARS
Target/Specificity:
The synthetic peptide sequence used to generate the antibody AP7845a was selected from the N-term region of human IARS. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Gene Name: IARS1 (HGNC:5330)
Gene ID: 3376
Primary Accession: P41252
Format: Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
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