IASPP polyclonal, anti-human, mouse, rat

Background:
Regulator that plays a central role in regulation of apoptosis and transcription via its interaction with NF-kappa-B and p53/TP53 proteins. Blocks transcription of HIV-1 virus by inhibiting the action of both NF-kappa-B and SP1. Also inhibits p53/TP53 function, possibly by preventing the association between p53/TP53 and ASPP1 or ASPP2, and therefore suppressing the subsequent activation of apoptosis.

Synonyms: IASPP, NKIP1, RAI, RAI4

Cellular Location: Cytoplasm Nucleus

Immunogen:
A synthetic peptide of human IASPP

Gene Symbol: IASPP

Gene ID: 10848

Swiss prot: Q8WUF5

Calculated MW: 120kDa

Recommended dilution:
WB 1:3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.03% Proclin300, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.