IBA57 Polyclonal Antibody

Background:
The protein encoded by this gene localizes to the mitochondrion and is part of the iron-sulfur cluster assembly pathway. The encoded protein functions late in the biosynthesis of mitochondrial 4Fe-4S proteins. Defects in this gene have been associated with autosomal recessive spastic paraplegia-74 and with multiple mitochondrial dysfunctions syndrome-3. Two transcript variants encoding different isoforms have been found for this gene. The smaller isoform is not likely to be localized to the mitochondrion since it lacks the amino-terminal transit peptide.

Synonyms:
C1orf69, CAF17, Chromosome 1 open reading frame 69, FLJ12734, FLJ13849, IBA57, IBA57 homolog iron sulfur cluster assembly, IBA57 iron sulfur cluster assembly homolog , IBA57 iron sulfur cluster assembly homolog (S. cerevisiae), IBA57, S. cerevisiae, homolog of, Iron sulfur cluster assembly factor for biotin synthase and aconitase like , iron-sulfur cluster assembly factor for biotin synthase- and aconitase-like mitochondrial proteins, with a mass of 57kDa, Iron-sulfur cluster assembly factor homolog, Mitochondrial proteins with a mass of 57kDa, MMDS3, Putative transferase C1orf69 mitochondrial, Putative transferase CAF17, mitochondrial, SPG74

Immunogen: Synthetic peptide of human IBA57

Swissprot: Q5T440
Gene Accession: NP001010867

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.9 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.