IBTK polyclonal (Center), anti-human

IBTK polyclonal (Center), anti-human

€0.00
In stock
SKU
AC-AP10731c
Catalog Number: AC-AP10731c
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB24652
Applications: FC, IHC-P, WB
Datasheet

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Background:
The protein encoded by this gene binds to Bruton's tyrosine kinase (BTK) and downregulates BTK's kinase activity. In addition, the encoded protein disrupts BTK-mediated calcium mobilization and negatively regulates the activation of nuclear factor-kappa-B-driven transcription.

Other Names:
Inhibitor of Bruton tyrosine kinase, IBtk, IBTK, BTKI, KIAA1417

Target/Specificity:
This IBTK antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-613 amino acids from the Central region of human IBTK.

Antigen Region:
586-613

Antigen Type: Synthetic Peptide

Gene Name: IBTK
Gene ID: 25998
Primary Accession: Q9P2D0
NCBI Accession: NP_056340.2
Other Accession: NP_056340.2
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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