ICAM1 (clone 6G12), anti-human
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In stock
SKU
BT-MCA2619
Catalog Number: BT-MCA2619
Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s):
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG1
Reactivity: human
Application(s):
Datasheet
Request Information
Background:
ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
Research Area: Immunology
Synonyms: BB2, CD54, P3.58, ICAM1
Immunogen: Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
ICAM1 is a 85-110 kDa single chain type 1 integral membrane glycoprotein with an extracellular domain of five immunoglobulin superfamily repeats, a transmembrane region and a cytoplasmic domain. It shares considerable amino acid sequence homology with ICAM3 and with ICAM2. ICAM1 is expressed by activated endothelial cells. It is detected on cells of many other lineages (e.g. epithelial cells, fibroblasts, chondrocytes, B lymphocytes, T lymphocytes (low), monocytes, macrophages, dendritic cells and neutrophils), with lower levels that increase in inflammation. ICAM1 is also detected in some carcinoma and melanoma cells. Soluble ICAM1 is detectable in the plasma and is elevated in patients with various inflammatory syndromes. It is the receptor for rhinoviruses and malaria.
Research Area: Immunology
Synonyms: BB2, CD54, P3.58, ICAM1
Immunogen: Purified recombinant fragment of human ICAM1(28-480aa) expressed in E. Coli.
Formulation: Ascitic fluid containing 0.03% sodium azide.
Storage:
4°C|-20°C for long term storage
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