ICSBP1 / IRF8 polyclonal, anti-human

Background:
Interferon consensus sequence-binding protein (ICSBP) is a transcription factor of the interferon (IFN) regulatory factor (IRF) family. Proteins of this family are composed of a conserved DNA-binding domain in the N-terminal region and a divergent C-terminal region that serves as the regulatory domain. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFN-alpha and IFN-beta. IRF family proteins also control expression of IFN-alpha and IFN-beta-regulated genes that are induced by viral infection.

Other Names:
Interferon regulatory factor 8, IRF-8, Interferon consensus sequence-binding protein, H-ICSBP, ICSBP, IRF8, ICSBP1

Antigen Types:
Synthetic Peptide

Gene Name:
IRF8 {ECO:0000303|PubMed:21524210, ECO:0000312|HGNC:HGNC:5358}
Gene ID:
3394
Primary Accession: Q02556
Other Accession: NP_002154;3394;15900 (mouse);