ICT1 polyclonal (C-term), anti-human

ICT1 polyclonal (C-term), anti-human

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In stock
SKU
AC-AP20382b
Catalog Number: AC-AP20382b
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB42881
Applications: IHC-P, WB
Datasheet

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Background:
Essential peptidyl-tRNA hydrolase component of the mitochondrial large ribosomal subunit. Acts as a codon-independent translation release factor that has lost all stop codon specificity and directs the termination of translation in mitochondrion, possibly in case of abortive elongation. May be involved in the hydrolysis of peptidyl-tRNAs that have been prematurely terminated and thus in the recycling of stalled mitochondrial ribosomes.

Other Names:
Peptidyl-tRNA hydrolase ICT1, mitochondrial, 39S ribosomal protein L58, mitochondrial, MRP-L58, Digestion substraction 1, DS-1, Immature colon carcinoma transcript 1 protein, ICT1, DS1

Target/Specificity:
This ICT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 153-179 amino acids from the C-terminal region of human ICT1.

Antigen Region:
153-179

Antigen Type: Synthetic Peptide

Gene Name: MRPL58 (HGNC:5359)
Gene ID: 3396
Primary Accession: Q14197
NCBI Accession: NP_001536.1
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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