ID1 polyclonal antibody, anti-human, mouse, rat

Background:
The protein encoded by this gene is a helix-loop-helix (HLH) protein that can form heterodimers with members of the basic HLH family of transcription factors. The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts. This protein may play a role in cell growth| senescence| and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and nuclear signaling

Synonyms: DNA-binding protein inhibitor ID-1 (Class B basic helix-loop-helix protein 24, bHLHb24, Inhibitor of DNA binding 1)

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year