IDE/Insulysin monoclonal, anti-human, mouse, rat
€455.00
In stock
SKU
AC-ABO13269
Catalog Number: AC-ABO13269
Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC
Datasheet
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Size: 100 µl
Isotype: Rabbit IgG
Applications: WB, IHC
Datasheet
Request Information
Description: Anti-IDE/Insulysin Rabbit Monoclonal Antibody . Tested in WB, IHC applications. This antibody reacts with Human, Mouse, Rat.
Protein Function:
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia..
Other Names: Insulin-degrading enzyme, 3.4.24.56, Abeta-degrading protease, Insulin protease, Insulinase, Insulysin, IDE {ECO:0000303|PubMed:20364150, ECO:0000312|HGNC:HGNC:5381}
Clone Name(s):
Clone: AOOB-9
Subcellular Localization: Cytoplasm. Cell membrane. Secreted. Present at the cell surface of neuron cells. The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform.
Gene ID: 3416
Immunogen: A synthesized peptide derived from human IDE
Calculated MW: 117968
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
Protein Function:
Plays a role in the cellular breakdown of insulin, IAPP, glucagon, bradykinin, kallidin and other peptides, and thereby plays a role in intercellular peptide signaling. Degrades amyloid formed by APP and IAPP. May play a role in the degradation and clearance of naturally secreted amyloid beta-protein by neurons and microglia..
Other Names: Insulin-degrading enzyme, 3.4.24.56, Abeta-degrading protease, Insulin protease, Insulinase, Insulysin, IDE {ECO:0000303|PubMed:20364150, ECO:0000312|HGNC:HGNC:5381}
Clone Name(s):
Clone: AOOB-9
Subcellular Localization: Cytoplasm. Cell membrane. Secreted. Present at the cell surface of neuron cells. The membrane-associated isoform is approximately 5 kDa larger than the known cytosolic isoform.
Gene ID: 3416
Immunogen: A synthesized peptide derived from human IDE
Calculated MW: 117968
Purification: Affinity-chromatography
Format: Liquid
Contents: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol, 0.4-0.5mg/ml BSA.
Concentration (mg/ml): Actual concentration vary by lot. Use suggested dilution ratio to decide dilution procedure.
Storage: Store at -20°C for one year. For short term storage and frequent use, store at 4°C for up to one month. Avoid repeated freeze-thaw cycles.
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