IDH3B polyclonal, anti-human, rat
€305.00
In stock
SKU
BS60617
Background:
IDH3B (Isocitrate dehydrogenase 3 (NAD+) b, NAD(+)-specific ICDH) is a 384 amino acid protein encoded by the human gene IDH3B. IDH3B belongs to the isocitrate and isopropylmalate dehydrogenases family and can bind one magnesium or manganese ion per subunit. It is usually found in the mitochondrion as a heterooligomer of subunits a, b, and g in the apparent ratio of 2:1:1. Human NAD-dependent isocitrate dehydrogenase (IDH) is allosterically activated by ADP by lowering the Km for isocitrate. NAD-dependent isocitrate dehydrogenase is a tricarboxylic acid cycle enzyme that produces 2-oxoglutarate, an organic acid required by the glutamine synthetase/glutamate synthase cycle to assimilate ammonium.
Alternative Name:
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta NAD(+)-specific ICDH subunit beta, DH3B
Application Dilution: WB: 1:500~1:1000
Specificity: IDH3B polyclonal antibody detects endogenous levels of IDH3B protein.
Immunogen:
A synthetic peptide corresponding to residues in Human IDH3B
MW: ~ 42 kDa
Swis Prot.: O43837
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
IDH3B (Isocitrate dehydrogenase 3 (NAD+) b, NAD(+)-specific ICDH) is a 384 amino acid protein encoded by the human gene IDH3B. IDH3B belongs to the isocitrate and isopropylmalate dehydrogenases family and can bind one magnesium or manganese ion per subunit. It is usually found in the mitochondrion as a heterooligomer of subunits a, b, and g in the apparent ratio of 2:1:1. Human NAD-dependent isocitrate dehydrogenase (IDH) is allosterically activated by ADP by lowering the Km for isocitrate. NAD-dependent isocitrate dehydrogenase is a tricarboxylic acid cycle enzyme that produces 2-oxoglutarate, an organic acid required by the glutamine synthetase/glutamate synthase cycle to assimilate ammonium.
Alternative Name:
Isocitrate dehydrogenase [NAD] subunit beta, mitochondrial, Isocitric dehydrogenase subunit beta NAD(+)-specific ICDH subunit beta, DH3B
Application Dilution: WB: 1:500~1:1000
Specificity: IDH3B polyclonal antibody detects endogenous levels of IDH3B protein.
Immunogen:
A synthetic peptide corresponding to residues in Human IDH3B
MW: ~ 42 kDa
Swis Prot.: O43837
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1 mg/ml in Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
| Is Featured? | No |
|---|
Write Your Own Review