IDH3G Polyclonal Antibody

Background:
Isocitrate dehydrogenases catalyze the oxidative decarboxylation of isocitrate to 2-oxoglutarate. These enzymes belong to two distinct subclasses, one of which utilizes NAD(+) as the electron acceptor and the other NADP(+). Five isocitrate dehydrogenases have been reported: three NAD(+)-dependent isocitrate dehydrogenases, which localize to the mitochondrial matrix, and two NADP(+)-dependent isocitrate dehydrogenases, one of which is mitochondrial and the other predominantly cytosolic. NAD(+)-dependent isocitrate dehydrogenases catalyze the allosterically regulated rate-limiting step of the tricarboxylic acid cycle. Each isozyme is a heterotetramer that is composed of two alpha subunits, one beta subunit, and one gamma subunit.

Research Area: Cancer, Metabolism, Signal Transduction

Synonyms:
H IDHG, IDH gamma, IDH3G, IDH3G, Isocitrate dehydrogenase [NAD] subunit gamma, Isocitrate dehydrogenase [NAD] subunit gamma, mitochondrial, Isocitrate dehydrogenase 3 (NAD+) gamma, Isocitric dehydrogenase, Isocitric dehydrogenase subunit gamma, mitochondrial, NAD (H) specific isocitrate dehydrogenase gamma subunit, NAD(+) specific ICDH, NAD(+)-specific ICDH subunit gamma, NAD+ specific ICDH, OTTHUMP00000025984, OTTHUMP00000025985, OTTHUMP00000025987, OTTHUMP00000025988, OTTHUMP00000214764

Immunogen: Recombinant protein of human IDH3G

Swissprot: P51553
Gene Accession: BC001902

Calculated MW: 43 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Concentration: 0.3 mg/mL
Dilution: WB 1:500-1:2000, IHC 1:25-1:100

Storage:
Store at -20°C. Avoid freeze / thaw cycles.

Alternative for product with catalog number:
sc-55677/sc-55680