IDS polyclonal, anti-human

Background:
Iduronate-2-sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X-chromosome gene that result in enzymatic deficiency lead to the sex-linked Mucopolysaccharidosis Type II, also known as Hunter Syndrome. Iduronate-2-sulfatase has a strong sequence similarity with human arylsulfatases A, B, and C, and human glucosamine-6-sulfatase. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described.

Other Names:
Iduronate 2-sulfatase, 3.1.6.13, Alpha-L-iduronate sulfate sulfatase, Idursulfase, Iduronate 2-sulfatase 42 kDa chain, Iduronate 2-sulfatase 14 kDa chain, IDS, SIDS

Antigen Types:
Synthetic Peptide

Gene Name:
IDS
Gene ID:
3423
Primary Accession: P22304
Other Accession: NP_000193;3423;