IF5A1 polyclonal antibody, anti-human, mouse, rat

Background:
The precise role of eIF-5A in protein biosynthesis is not known but it functions by promoting the formation of the first peptide bond.|PTM:eIF-5A seems to be the only eukaryotic protein to have an hypusine residue which is a post-translational modification of a lysine by the addition of a butylamino group (from spermidine).|Belongs to the eIF-5A family.|subunit:Found in a complex with Ran and XPO4. The hypusine modification increases the interaction with XPO4.|tissue specificity:Expressed in umbilical vein endothelial cells and several cancer cell lines (at protein level).|

Research Area: Epigenetics and nuclear signaling

Synonyms: Eukaryotic translation initiation factor 5A-1 (eIF-5A-1, eIF-5A1, Eukaryotic initiation factor 5A isoform 1, eIF-5A, Rev-binding factor, eIF-4D)

Immunogen: The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage:
-20°C for 1 year