IF6 Polyclonal Antibody
€0.00
In stock
SKU
ELK-ES9001
Catalog Number: ELK-ES9001
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Reactivity: Human, Mouse, Rat
Applications: WB, ELISA
Information
Request Manual ELK-
Questions? Contact us!
Background:
eukaryotic translation initiation factor 6(EIF6) Homo sapiens Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],
Immunogen: Synthesized peptide derived from human protein . at AA range: 180-260
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 26
GeneID: EIF6 EIF3A ITGB4BP OK/SW-cl.27
Storage: -20°C/1 year
NOTE: For Research Use Only
eukaryotic translation initiation factor 6(EIF6) Homo sapiens Hemidesmosomes are structures which link the basal lamina to the intermediate filament cytoskeleton. An important functional component of hemidesmosomes is the integrin beta-4 subunit (ITGB4), a protein containing two fibronectin type III domains. The protein encoded by this gene binds to the fibronectin type III domains of ITGB4 and may help link ITGB4 to the intermediate filament cytoskeleton. The encoded protein, which is insoluble and found both in the nucleus and in the cytoplasm, can function as a translation initiation factor and prevent the association of the 40S and 60S ribosomal subunits. Multiple non-protein coding transcript variants and variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jun 2012],
Immunogen: Synthesized peptide derived from human protein . at AA range: 180-260
Isotype: Rabbit
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1 mg/ml
Observed band: 26
GeneID: EIF6 EIF3A ITGB4BP OK/SW-cl.27
Storage: -20°C/1 year
NOTE: For Research Use Only
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