IFI16 Polyclonal Antibody

Background:
This gene encodes a member of the HIN-200 (hematopoietic interferon-inducible nuclear antigens with 200 amino acid repeats) family of cytokines. The encoded protein contains domains involved in DNA binding, transcriptional regulation, and protein-protein interactions. The protein localizes to the nucleoplasm and nucleoli, and interacts with p53 and retinoblastoma-1. It modulates p53 function, and inhibits cell growth in the Ras/Raf signaling pathway. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Cancer, Cell Biology, Epigenetics and Nuclear Signaling, Metabolism

Synonyms:
IFI16, IFNGIP1, PYHIN2

Immunogen: Recombinant fusion protein of human IFI16 (NP_005522.2).

Swissprot: Q16666
Gene ID: 3428

Calculated MW: 75 kDa/82 kDa/88 kDa
Observed MW: 88 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:200"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.