IFITM2 Polyclonal Antibody

Background:
IFITM2, also named as 1-8D, belongs to the CD225 family. It is an IFN-induced antiviral protein that mediates cellular innate immunity to at least three major human pathogens, namely influenza A H1N1 virus, West Nile virus (WNV), and dengue virus (WNV), by inhibiting the early step(s) of replication. IFITM2 induces cell cycle arrest and mediates apoptosis by caspase activation and in p53-independent manner. It is overexpressed in colon carcinoma. IFITM2 is a novel pro-apoptotic gene that will provide new insights into the regulated cellular pathways to death. This antibody is specific to IFTIM2.

Research Area: Cancer, Immunology

Synonyms:
1 8D, Dispanin subfamily A member 2c, DSPA2c, IFITM 2, Interferon induced transmembrane protein 2 (1 8D), Interferon induced transmembrane protein 2, Interferon inducible protein 1 8D

Immunogen: Fusion protein of human IFITM2

Swissprot: Q01629
Gene Accession: BC009696

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.72 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.