IFN-R1 polyclonal, anti-human, mouse, rat
€388.00
In stock
SKU
BS7140
Background:
The type I interferons, IFN-α and IFN-β, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-α and IFN-β appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor. This distinct receptor, IFN-αR, is only weakly responsive to type I interferons, in contrast to IFN-α/βR, which binds to and responds effectively to IFN-β and to several of the IFN-α subtypes. IFN-α/βR is expressed as two alternatively spliced transcripts, designated IFN-α/βRα (IFN-α/βR1) and IFN-α/βRβ (IFN- α/βR2), both of which are involved in signal transduction and ligand binding.
Alternative Name:
Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1, IFNAR, IFNR1, IFN R1, IFN-α/βRα,IFN-α/βR1, IFN α/βRα, IFNα/βR1, IFNα/β-Rα, IFNα/β R1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: IFN-R1 polyclonal antibody detects endogenous levels of IFN-R1 protein.
Immunogen:
Recombinant full length Human IFN-R1.
MW: ~ 64 kDa
Swis Prot.: P17181
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The type I interferons, IFN-α and IFN-β, are a group of structurally and functionally related proteins that are induced by either viruses or double-stranded RNA and are defined by their ability to confer an antiviral state in cells. IFN-α and IFN-β appear to compete with one another for binding to a common cell surface receptor, while immune IFN (IFN-γ) binds to a distinct receptor. This distinct receptor, IFN-αR, is only weakly responsive to type I interferons, in contrast to IFN-α/βR, which binds to and responds effectively to IFN-β and to several of the IFN-α subtypes. IFN-α/βR is expressed as two alternatively spliced transcripts, designated IFN-α/βRα (IFN-α/βR1) and IFN-α/βRβ (IFN- α/βR2), both of which are involved in signal transduction and ligand binding.
Alternative Name:
Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1, IFNAR1, IFNAR, IFNR1, IFN R1, IFN-α/βRα,IFN-α/βR1, IFN α/βRα, IFNα/βR1, IFNα/β-Rα, IFNα/β R1,
Application Dilution: WB: 1:500~1:2000, IHC: 1:50~1:200
Specificity: IFN-R1 polyclonal antibody detects endogenous levels of IFN-R1 protein.
Immunogen:
Recombinant full length Human IFN-R1.
MW: ~ 64 kDa
Swis Prot.: P17181
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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