IFNA1/IFNA13 Polyclonal Antibody

Background:
IFNA1 (interferon-alpha) is a member of the Type I IFN (1) family best known for their antiviral activity. It is a key cytokine regulating the activity of B cells, T-helper cells (Th cells), cDCs and natural killer cells (NK cells). Interferon-alpha induces B cell maturation into plasma cells and immunoglobulin production. Interferon-alpha plays an important role in the pathogenesis of systemic lupus erythematosus (SLE). Interferon-alpha was the first cytokine to show clinical benefit in the treatment of certain types of cancer, including melanoma, chronic myelogenous leukemia, and renal cancer.

Research Area: Cancer, Immunology

Synonyms:
IFL, IFN alpha, IFN alpha 1/13, IFN alpha 1b, IFN alphaD, IFN, IFN-alpha-1/13, IFNA@, IFNA1, IFNA1, IFNA13, Interferon alpha 1, Interferon alpha-1/13, Interferon alpha-D, Interferon alpha1, Interferon, alpha 13, LeIF D

Immunogen: Synthetic peptide of human IFNA1/IFNA13

Swissprot: P01562
Gene Accession: NP008831

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 0.96 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.