Ifna1 polyclonal, anti-human, mouse, rat

Background:
The genes encoding type I interferons (IFNs), which include 14 IFN-α genes (two of which are IFN-α1 and IFN-α13), one IFN-β gene, one IFN-w (also known as IFN-α II1) gene and a number of IFN-w pseudogenes, are clustered on human chromosome 9. IFN-α and -β are cytokines that are widely known to induce potent antiviral activity. They exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.

Alternative Name:
IFN-alpha-1/13, LeIF D, IFNA1, IFNA13, IFN-alpha-14, IFN14, IFNA14, Interferon alpha 14, Interferon alpha H, Interferon alpha-14, Interferon alpha-H, Interferon lambda-2-H, Interferon lambda2H, LeIF H, LeIFH, MGC125756, MGC125757,

Application Dilution:
WB:1:500
ICC:1:50-1:200
IHC:1:50-1:200
FC:1:50-1:100

Specificity: Ifna1 polyclonal antibody detects endogenous levels of Ifna1 protein.

Immunogen:
Peptide

MW: 22 kDa

Swiss-Prot: P01562(Human) P01572(Mouse) P05011(Rat)

Purification & Purity:
Peptide affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.