IFNAR2 Polyclonal Antibody

Background:
The protein encoded by this gene is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. Multiple transcript variants encoding at least two different isoforms have been found for this gene.

Research Area: Cancer, Epigenetics and Nuclear Signaling, Immunology, Signal Transduction

Synonyms:
IFNAR2, IFN-R, IFN-alpha-REC, IFNABR, IFNARB, IMD45

Immunogen: Recombinant fusion protein of human IFNAR2 (NP_997467.1).

Swissprot: P48551
Gene ID: 3455

Calculated MW: 27 kDa/37 kDa/57 kDa
Observed MW: 58 kDa

Purification Method: Affinity purification

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3

Concentration: 1 mg/mL
Dilution: "WB 1:500-1:2000 IHC 1:50-1:100 IF 1:50-1:100"

Storage:
Store at -20°C. Avoid freeze / thaw cycles.