IFNB1 polyclonal, anti-human, mouse, rat
€305.00
In stock
SKU
BS60295
Background:
The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.
Alternative Name:
Interferon beta, Interferon β, IFN-beta, IFN-β, IFNβ, Fibroblast interferon, IFB, IFNB
Application Dilution: WB: 1:500~1:1000
Specificity: IFNB1 polyclonal antibody detects endogenous levels of IFNB1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human IFNB1.
MW: ~ 26 kDa
Swis Prot.: P01574
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
The genes encoding type I interferons (IFNs), which include 14 IFN-α genes, one IFN-β gene, one IFN-w (also known as IFN-α II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-α and -β are cytokines that are widely known to induce potent antiviral activity. IFN-α and -β exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-α, IFN-β or IFN-γ, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-αR) interacts with IFN-α, IFN-β and IFN-w, and seems to be a multisubunit receptor.
Alternative Name:
Interferon beta, Interferon β, IFN-beta, IFN-β, IFNβ, Fibroblast interferon, IFB, IFNB
Application Dilution: WB: 1:500~1:1000
Specificity: IFNB1 polyclonal antibody detects endogenous levels of IFNB1 protein.
Immunogen:
A synthetic peptide corresponding to residues in Human IFNB1.
MW: ~ 26 kDa
Swis Prot.: P01574
Purification & Purity:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Format:
1mg/ml in PBS with 0.1% Sodium Azide, 50% Glycerol.
Storage:
Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
For research use only, not for use in diagnostic procedure.
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