IFNB1 Polyclonal Antibody

Background:
This gene encodes a cytokine that belongs to the interferon family of signaling proteins, which are released as part of the innate immune response to pathogens. The protein encoded by this gene belongs to the type I class of interferons, which are important for defense against viral infections. In addition, type I interferons are involved in cell differentiation and anti-tumor defenses. Following secretion in response to a pathogen, type I interferons bind a homologous receptor complex and induce transcription of genes such as those encoding inflammatory cytokines and chemokines. Overactivation of type I interferon secretion is linked to autoimmune diseases. Mice deficient for this gene display several phenotypes including defects in B cell maturation and increased susceptibility to viral infection.

Research Area: Cancer, Cardiovascular, Immunology

Synonyms:
beta-interferon, Fibroblast interferon, IFB, IFF, IFN beta, IFN-beta, IFNB 1, IFNB, IFNB, IFNB1, Interferon beta 1 fibroblast, Interferon beta, Interferon beta precursor, MGC96956

Immunogen: Synthetic peptide of human IFNB1

Swissprot: P01574
Gene Accession: NP002167

Purification Method: Antigen affinity purification

Buffer: PBS with 0.05% NaN3 and 40% Glycerol, pH7.4

Concentration: 1.1 mg/mL
Dilution: IHC 1:30-1:150, ELISA 1:5000-1:10000

Storage:
Store at -20°C. Avoid freeze / thaw cycles.