IFT74 polyclonal, anti-human, mouse, rat

Background:
This gene encodes a core intraflagellar transport (IFT) protein which belongs to a multi-protein complex involved in the transport of ciliary proteins along axonemal microtubules. IFT proteins are found at the base of the cilium as well as inside the cilium, where they assemble into long arrays between the ciliary base and tip. This protein, together with intraflagellar transport protein 81, binds and transports tubulin within cilia and is required for ciliogenesis. Naturally occurring mutations in this gene are associated with amyotrophic lateral sclerosis--frontotemporal dementia and Bardet-Biedl Syndrome.

Synonyms: BBS20, CCDC2, CMG-1, CMG1

Cellular Location: Cell projection Cytoplasmic vesicle cilium

Immunogen:
Recombinant protein of human IFT74

Gene Symbol: IFT74

Gene ID: 80173

Swiss prot: Q96LB3

Calculated MW: 69kDa

Recommended dilution:
WB 1:1000-3000

Purity:
Affinity purification

Storage Buffer:
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Storage:
Store at -20℃. Avoid freeze / thaw cycles.