IGF1 Receptor (IGF1R) polyclonal (C-term), anti-human, mouse, rat
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In stock
SKU
AC-AP7649B
Catalog Number: AC-AP7649B
Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01458
Applications: IHC-P, WB
Datasheet
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Size: 80 µl, 400 µl
Isotype: Rabbit IgG
Clone Name: RB01458
Applications: IHC-P, WB
Datasheet
Request Information
Background:
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Other Names:
Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor, CD221, Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain, IGF1R
Target/Specificity:
This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1335-1366 amino acids from the C-terminal region of human IGF1 Receptor (IGF1R).
Antigen Region:
1335-1366
Antigen Type: Synthetic Peptide
Gene Name: IGF1R
Gene ID: 3480
Primary Accession: P08069
NCBI Accession: NP_000866.1
Other Accession: Q05688
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
The IGF1R receptor binds insulin-like growth factor with a high affinity and plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. The protein possess tyrosine kinase activity.
Other Names:
Insulin-like growth factor 1 receptor, Insulin-like growth factor I receptor, IGF-I receptor, CD221, Insulin-like growth factor 1 receptor alpha chain, Insulin-like growth factor 1 receptor beta chain, IGF1R
Target/Specificity:
This IGF1 Receptor (IGF1R) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1335-1366 amino acids from the C-terminal region of human IGF1 Receptor (IGF1R).
Antigen Region:
1335-1366
Antigen Type: Synthetic Peptide
Gene Name: IGF1R
Gene ID: 3480
Primary Accession: P08069
NCBI Accession: NP_000866.1
Other Accession: Q05688
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
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