IGF1R (clone 3B4E3), anti-
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In stock
SKU
BT-MCA4754
Catalog Number: BT-MCA4754
Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity:
Application(s): WB, FCM
Datasheet
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Size(s): 50μL, 100μL
Isotype: Mouse IgG2a
Reactivity:
Application(s): WB, FCM
Datasheet
Request Information
Background:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Area: Others
Synonyms: IGFR, CD221, IGFIR, JTK13
Immunogen: Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Research Area: Others
Synonyms: IGFR, CD221, IGFIR, JTK13
Immunogen: Purified recombinant fragment of human IGF1R (AA: extra(741-935)) expressed in E. Coli.
Formulation: Purified antibody in PBS with 0.05% sodium azide
Storage:
4°C|-20°C for long term storage
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