IGF2 (clone 8H1), anti-human

Background:
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Research Area: Signal transduction, Cancer, Developmental biology, Stem cells

Synonyms: IGF-II, PP9974, C11orf43, FLJ22066, FLJ44734

Immunogen: Purified recombinant fragment of human IGF2 (AA: 25-180) expressed in E. Coli.

Formulation: Purified antibody in PBS with 0.05% sodium azide

Storage:
4°C|-20°C for long term storage