IGF2 polyclonal, anti-human

Background:
IGF-II (Insulin-like growth factor II, also multiplication-stimulating polypeptide/MSP and somatomedin-A) is a secreted 8 kDa polypeptide that belongs to the insulin family of peptide growth factors. It is part of a complex system of growth and metabolic-regulating proteins that is particularly important during development. It has been associated with nervous system proliferation and differentiation, myelination, adrenal cortical proliferation, and skeletal growth and differentiation. In human, IGF-II is primarily synthesized by the liver, and circulates at high levels in both fetus and adult. In rodent, however, IGF-II levels drop after the perinatal period, an effect attributed to the lack of a key gene promoter. This may indicate that postnatally, IGF-II has either a limited, or local effect only in rodent.

Alternative Name:
IGF-II, C11orf43, IGF 2, IGF II, IGF-II, IGF2, IGF2, IGFII, INSIGF, insulin like growth factor 2 (somatomedin A), Insulin like Growth Factor 2, Insulin like growth factor II, Insulin like growth factor II precursor, Insulin like growth factor type 2, pp9974, Preptin, putative insulin like growth factor II associated protein, Somatomedin A, Somatomedin-A,

Application Dilution:
WB:1:1,000
ICC:1:100-1:500
IHC:1:50-1:200

Specificity: IGF2 polyclonal antibody detects endogenous levels of IGF2 protein.

Immunogen:
recombinant protein

MW: 11 kDa

Swiss-Prot: P01344(Human)

Purification & Purity:
ProA affinity purified

Format:
Rabbit IgG, 1mg/ml in PBS with 0.02% sodium azide, 50% glycerol, pH7.2

Storage:
Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

For research use only, not for use in diagnostic procedure.