IGF2 polyclonal (Center R54), anti-human, mouse

IGF2 polyclonal (Center R54), anti-human, mouse

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In stock
SKU
AC-AP11220c
Catalog Number: AC-AP11220c
Size: 50 µl, 200 µl
Isotype: Rabbit IgG
Clone Name: RB18750
Applications: WB, IHC-P, FC
Datasheet

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Background:
This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Other Names:
Insulin-like growth factor II, IGF-II, Somatomedin-A, Insulin-like growth factor II, Insulin-like growth factor II Ala-25 Del, Preptin, IGF2

Target/Specificity:
This IGF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 39-68 amino acids from the Central region of human IGF2.

Antigen Region:
39-68

Antigen Type: Synthetic Peptide

Gene Name: IGF2
Gene ID: 3481
Primary Accession: P01344
NCBI Accession: NP_000603.1;NP_001007140.2;NP_001121070.1
Other Accession: NP_000603
Format: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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